SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    431579, 431580, 431581, 431582, 431583, 
    431584, 431585, 431586
  ) 
  AND feature_id IN (626, 860) 
  AND lang_code = 'en'

Query time 0.00089

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "7.45"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 16,
      "rows_produced_per_join": 16,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "4.25",
        "eval_cost": "3.20",
        "prefix_cost": "7.45",
        "data_read_per_join": "12K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`product_id` in (431579,431580,431581,431582,431583,431584,431585,431586)) and (`webmarco`.`cscart_product_features_values`.`feature_id` in (626,860)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
431579 626 7161
431580 626 7168
431581 626 7162
431582 626 7163
431583 626 7164
431584 626 7165
431585 626 7166
431586 626 7167
431579 860 64475
431580 860 64475
431581 860 64475
431582 860 64475
431583 860 64475
431584 860 64475
431585 860 64475
431586 860 64475