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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd4423c8d1ebe52ede414ed233082abbe1e4460ca21edad85464bfbb583970f' 
  AND token = 'RUTT5P+oUxlRp0XK2PEH9uQyYbYSE7hAUcWDDmSjLkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}