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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6d2bc084a04b7234e5d3eba22aab5c1d0bc9317b9b594f409710a8d659baab' 
  AND token = 'lQdG2cCjJX8TVh8PFBWtncJxUFYPbYHCfCxCxeJlNoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}