SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454e0c8deb83a7468787b54c2e97809b463020fb49265c0feeb0afd8fa28cd42' 
  AND token = 'SFqnC8VmjanY2sNcDiT2gQED7ZS72BsHd58zLl9fp38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}