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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494e6ade739f73cb7fc5f49e25a7cb1a0b8a7c69ffbbef19de098b232d923761' 
  AND token = 'A7IHLLlxDcWE3sTo3bZ7Vewl9Dt3mg+vykQPgGaRzEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}