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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a4e274f83fea4dc18e15f773e1c3650fd8e8b92aa51b537507a4591497c4d3' 
  AND token = 'tC4Fq7lCymRsBf+V0ejS+jOUEW2MskmMFL2ZRBznUUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}