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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e66a177d5c3c6143c0061714bfd7cf25526f78ad025c6e832c1233ccb2b4da1' 
  AND token = 'IIP8IwL8MVTwLqns/5KNWWfLsCTL7RlD3t6/kZrJhvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}