SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bbe0a9f57bc004278ade82d66cb6dbdc13878b72cf4ab3f971035458402bc85' 
  AND token = 'RuAqZeAf4RLiDR/1N2TTjRFpzyyCG3gz8HZepsVXKj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}