SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee160f2215659084aadf4b81a6c3bcd204a1346ba486fd66d96b043799e69910' 
  AND token = 'datO0G9a5mnjiXxmlzRBpkuiHiQe0SCHdm4hMhUtl9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}