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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd71aa3b7095bc663e0711e908f57295b2c807ef440c5e1d014fce8254792c0a3' 
  AND token = 'vUxW4EjE2QWTB7w8ypin1zwMxRFCBQ9r0WRnUzGy/Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}