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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bda38410e95c7a642af6ac7aab390c94a2568aa0aacb3ef3a785f7e0f12b7f' 
  AND token = 'exJxh2LrShUxtnGtQK6LX7+c3h2FJ18/OV0LIytU4/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}