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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc8bf8da3f42abb7ed99d2fcdba4ff968a9efddd13ccc6743239b48f12effbf4' 
  AND token = 'Jc5pSOWOGRVgATmNSU22LbXr9wrFHO6YuPS3ZZFyxD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}