SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2fbdb7bc549dec0409eeccee329eff4064c1a34eded35bcd0dfe29fa11ffc7' 
  AND token = 'MFTPDMwKxqeO9152meqbIGlcgfTawmMazvg4kkvY6Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}