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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '906acb37b2fd2ac0e0d981e08a10bccac8d29eb781299c3b888ed4a5cc6e7725' 
  AND token = 'e8VDkyFbPA2Mu+nWmaTEnMgb9lA0UMmJG3XiYfnf7gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}