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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc06aa39827afbfa115da4dffca1982c5136f156cc7cc3f10f0f3ea0446bcd4c' 
  AND token = 'Qa91TvTrwTs7T7uIRWpNXizclph4n0pF3DcJV7GhKxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}