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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9b0250df0cf5991b2343dfc8192c23f4cf33b1ca969330827f13dbcd357358' 
  AND token = 'F6L55Z19gN0ERmoPxxhwFfDyfyrD+XXy98QDQxwQWvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}