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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9834978ff1ed02d69d1a7f52544e76a79a1bde37e4ba46fb8352854d53574a71' 
  AND token = 'XQS10uk+4Clbi9Wdp9kpvANlQs02otQB2c3Yx1S4Ldg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}