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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c7cf9b649a7c5a10b151439cd0dfb1c8911c46aced57785c8af89c378fd66b' 
  AND token = 'O9wjk70ggF1101ybGnwQ3cyifZH36y1y5cKKQIDCSJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}