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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2684fbb4d1c57afb379d19f00033a0f4235fe20100f7b86d7393e3acd6225e' 
  AND token = '/xm+w9tOFhIBXwNlpWCd389nR77+0QuE2dRd9Ehqcek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}