SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f70b5d6cfdfa8c64c61ffac0f6dd4a87d165a82ce07f929901297f2b31a15f67' 
  AND token = 'xoJ+sykus1B8N1vSeMqzKTFnTe6mUDr+Vp0xaxbpLZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}