SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a745bcb60d4a0db0ed367b89c1d5b37c6d5c628abe9c3d03882e46641472aa5' 
  AND token = 'l0Pt9Smln+Vs0zEvwdzbOhqxop+1t++HyRPvPwvh00s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}