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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426e41d9074ea57afc200870007fc125388d046d81c3815215467b216a996299' 
  AND token = 'KzMvscTsi1bsH9Ng/ArWJ/WjSz2expnPyOStyu9XbwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}