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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e2d2bfee61e0e39f0b41c4e20e8402fa2ff7b31f761ec4803357de4463622c' 
  AND token = 'DQLizYuhS/XCIs0ImGHiGRoQT/POxLG7yv+L/GoDFAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}