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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2851f7b98172755a0ed8f112a7c8dae1dfb16e44c388ebc3dac6615e3ac1ab0' 
  AND token = 'EmP8NsAhnudMVdk6iJitsdxN+dO8E+aiAOCGPXYx8UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}