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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98488cced44bcd75921bbb95363c1378e86420d72e8cb9ce26b434c849b615e5' 
  AND token = 'px9mXcE+I6i4spUWl3kh9ibkI7UA9uItIoOvMXoK1XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}