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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c08afcfe761a729059cdcb966a76868b07c257d88d6e686b1cdd866affa496b7' 
  AND token = 'YNGm4C69uKqafJpRRmPHM1JsT+sb7QVjyBdkRZJwJms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}