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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2d4879e33d75c7f2a60c35d73c4a0f5fd5f333e3243636b07bcd9b8e5fc631' 
  AND token = 'ACmsI1tYmDcqtEuySsZNuNoJe4f9h7SzuNMuMIRQwIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}