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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee95ff9e82c25eaa031da6ca623734117b73003024c31f25912ed471cf9985fb' 
  AND token = 'G8OPaqNQTHj6ch9o+tnkVk1zODRKHIl7gr1WJiAYJ3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}