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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f57efa39ec4739f398a3258fec685506340f19f8b8172fc3c487f03f1f125cc' 
  AND token = 'T/IoQhCx8NT9Md3lFOCDv33sEdRMI/skZtz1ymL+USQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}