SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    431667, 431668, 431669, 431670, 431671
  ) 
  AND feature_id IN (626, 860) 
  AND lang_code = 'en'

Query time 0.00136

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "5.03"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 10,
      "rows_produced_per_join": 10,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "3.03",
        "eval_cost": "2.00",
        "prefix_cost": "5.03",
        "data_read_per_join": "7K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`product_id` in (431667,431668,431669,431670,431671)) and (`webmarco`.`cscart_product_features_values`.`feature_id` in (626,860)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
431667 626 67589
431668 626 67587
431669 626 7159
431670 626 7160
431671 626 7161
431667 860 64236
431668 860 64236
431669 860 64236
431670 860 64236
431671 860 64236