SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16d588bfc831113493459a20607de3b3e49a896e50f8ec6a65f617f4d850f66' 
  AND token = 'UvEiRko72Exvcj5OC5aYrHuHuBKHDBFnriZPPUKk2/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}