SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e34ec6ad411fd3bede35399e9c2d92cbcca0f1bb96849a7c6e9b9500d70a961' 
  AND token = 'UQauTCsvdx8UdOb9LhsLQLuw1Pq8dFGUhucc9aMUE0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}