SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e735c8370bb2d3eea1bfc30325c517027709918618feb2801556a30e6d4f69d2' 
  AND token = 'Lfd5Hg/HAWvag3J+e+MiXQwFjvcIkMzfEBG3rG+bV04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}