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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3586c5e6c582ab69d883e8378575110a1b102534fc2ec4b016e90031e3b62f5' 
  AND token = 'KxP6XcuUuFrh7OE0XdGGDaozrIJOEkttfh7nt9wCnpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}