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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3f538e2c95a088f8bb2fdf1300c3365b2f2271a0de7a4e287c851146951aca' 
  AND token = '3bLDtlGBSKAKe9pV37eJ5ov1JwGFfc6IScKLZqrdUcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}