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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d13584ba24f912c3541f72e3416f60c31d77baacd83e07f90a85183155b658' 
  AND token = 'Trnb/KbxGwi4SeOIEQlio342DBKiJK/8JzpXqHDQkl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}