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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df6fcfcbb4a9bf534267c0fc151eb036720bd5cf1d413241af847fbda42d7ab3' 
  AND token = 'wiu6pYXg78CcPIREYV5cKA2VrWTOmfeBVSz3dgDHsyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}