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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae599523160cdfcd5af9d4eb44f49075f4db6404aecb45157816a4a6db1bbcb' 
  AND token = 'gC+D3j+00nUMG9mAbwyvszM+FiiKV9YM7I5a7kohmEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}