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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adcb2c6d7ffa48d1166e02c07c0e2b572e6826008943022bda62d12e146c4d32' 
  AND token = 'JP8J7bZ+HSckzwOyjlOqMaQe7qGL6rwreTe00tgPkAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}