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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0460490000c388ea2b5956adf172b2be0dd528ad149a62f62950537606ed5925' 
  AND token = 'LMih4/g5/Qc8MD9y/f7ZpMFmAgt5gOU6BQOyj0Xgwhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}