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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818b8b1aa2af0dde99c20339752d2255274510032f3187e151a8b366a8eccd77' 
  AND token = 'adeE0e+eXVFMa/SAv/aj+PkMbeKrc7axNxcb0nPfIrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}