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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c02c00092e1d155aa04a7436eca1f0b1956c5dc1530229f94a66dfd802f410' 
  AND token = 'JMqUxemIzUkHdjXcnaj7eZHQzV2shRhV8NeRg/b7uR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}