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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '085d49c05bdf6facb22ff2c4cbeb4c2aa7b7b13fa212abf64bd63d52d7e0d522' 
  AND token = 'P8NFnsxia0jy/kNwgsdiIzQnU9FSg+crOQxxOFAgnxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}