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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d0a83bf568aadd34f18e615e45274ed39f71336e3a6053cd60e7d8351492fe' 
  AND token = '6XQKl2i3uNHEsYeNhqcAsivTV6n9d1xxiVihIjP9RpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}