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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37366f6d973f6d713b9ec23c1e3d760f4f68d61cfbeed63c7e56fcfa0d5a6dc5' 
  AND token = 'HOpk5iGv6NCdzWgmBtbj8drqUDrPeF9kmc79TBqe8M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}