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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f580ff12300a54c06b0987903c16d5e9f407c5d3ec1a2f12ea5c989ce6e2d9f6' 
  AND token = 'vuMmF76eRdF09fVsf3P+7n0swe9EG2+MY6JDp9mjKIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}