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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f63f2ad80f87b9be725a6b343be94a889d9c4a4dfbe73a4525ea51b177f1c72' 
  AND token = 'MzbeeDygaL3FTox0cNlARR/40FH0UTb2jlxSvn6ho5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}