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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0186cf3cbb4cc9156b2575af68c6955dcb4b534328c795b0d4645eee8d6dffff' 
  AND token = 'soNdd98La197Xm2ClTUidfkdrYjab5tYRNMFOdF+kmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}