SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c714708121252aa4ef70b8496c3e998924bfcad265ded2b6c0ff00dd420ef1' 
  AND token = '78FOR+tg79ORAt/hIeKB/f9ui++413s7uBR+edE3efg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}