SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110c3f6ea102b36a1634f1ed8d3a72a01d00c9efe53cbf4cfb9d0100119bc740' 
  AND token = '0Fstr+vwiwkNVvmtgODAZcSeeRrOFuOmPy3mlEZHItE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}